Skyla IUD-Benefits, Risks, and Comparisons

Skyla IUD hormones are a form of birth control that many women choose for its convenience. Once placed in the uterus, it slowly releases hormones to prevent pregnancy for up to three years.

The Skyla intrauterine device (IUD) is filled with levonorgestrel. This female hormone can cause changes in your cervical mucus and uterine lining. It makes it nearly impossible for sperm to reach the uterus and hinders a fertilized egg from attaching to the uterus.

It is a plastic device with T-shaped a small size. It is placed in the uterus, slowly releasing the hormone to prevent pregnancy for three years. (Other types of levonorgestrel intrauterine systems release different amounts of hormone and are used for different lengths of time.)

How does Skyla work?

Skyla IUD releases a progestin hormone locally into your uterus at a slow but steady speed. As it is estrogen-free, so it is beneficial for up to 3 years period.

It has some other functions to do like:

  • thickening cervical mucus
  •  inhibiting sperm movement
  • reducing sperm survival
  • thinning the lining of your uterus.

This IUD performs all these actions at the same time to prevent pregnancy.

How to Choose the Right IUD?

You may come across five FDA-approved brands of IUDs:

  • Kyleena
  • Liletta
  • Mirena
  • ParaGard
  • Skyla

As you know that IUDs are considered among the most effective birth control options, so you should consider the differences between brands. It will be very helpful to know more about them and decide which IUD is right for you and, if so, what the reasons are.


There are a few things that all IUDs have in common.

In the broadest sense, all IUDs authorized by the United States Food and Drug Administration (FDA) are regarded as very effective birth control devices.

These could be used on their own, and they’re removable, which means you can get pregnant after removing the IUD.

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The main distinction among the IUDs is that all but one releases the hormone levonorgestrel (a progestin) to prevent pregnancy. In contrast, ParaGard, which is hormone-free, works because it is made of copper.

Skyla vs. Mirena 

Every day, Mirena and Skyla gradually release hormones into your body. 

Side Effects

To effectively prevent conception, these hormones can have three distinct effects:

  • They may cause you to ovulate less frequently.
  • They thicken cervical mucus, making it more difficult for sperm to enter your uterus.
  • They prevent the occurrence of sperm attaching to an egg and attaching to your uterus.

Skyla includes 13.5 mg of levonorgestrel, a progestin hormone (LNG). For the first 25 days, around 14 mcg of the hormone is secreted every day.

After that, the device releases decreasing levels of levonorgestrel until, after three years, it only releases around five mcg each day. After three years, it is necessary to replace it.

Mirena has a levonorgestrel content of 52 mg. When the device is first placed, around 20 mcg of this hormone is released every day. After five years, the rate reduces to around ten mcg per day as it approaches expiration and must be removed or replaced.

Skyla Vs. Kyleena

Other IUDs that gradually deliver a low dosage of hormones into your body are Liletta and Kyleena.

Kyleena has 19.5 mg of levonorgestrel and Liletta has 52 mg of levonorgestrel. Levonorgestrel is released in tiny levels by both of them. The amount of LNG released decreases with time, and by year five, the IUD should be removed.

However, as these are the newest IUDs, they haven’t been studied as extensively as previous IUDs. The FDA approved Liletta in February 2015. Kyleena received her approval in September of 2016.

Side effects

The side effects of Mirena and Skyla are the same. Changes in your period may occur, such as increased menstrual blood, pain, or the absence of a period. You may even want to consider:

  • acne
  • headache
  • breast tenderness
  • ovarian cysts disorder
  • depressed mood
  • pain in your abdomen or pelvic area

If you use ParaGard, you may have an allergic reaction to the copper. And some other side effects include:

  • heavy periods
  • discomfort
  • a longer period
  • backaches and cramps when you do not have a period

You see, all three devices can fall out or shift position. So here is the risk of getting pregnant. These could also tear your uterus. Some cases are there reporting about pelvic inflammatory disease, but this is rare.


The effectiveness of each IUD lasts a different period. People using Skyla should plan to remove and replace the IUD after three years if they wish to continue treatment.

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Mirena users should arrange to remove and replace the device every 5 to 6 years, depending on the device’s intended use.


Consult your doctor for further information on IUDs. They may provide you with further information about these devices and guide you in the direction of an IUD that may be suitable for you.

Frequently Asked Questions(FAQs)

1-What are the Skyla IUD side effects after two years?

  • irregular menstrual periods,
  • pain,
  • bleeding,
  • dizziness,
  • inflammation or itching of the vulva or vagina,
  • abdominal or pelvic pain,
  • changes in menstrual periods,
  • acne,

2-Why do some females using Skyla discontinue its operation?

Of the women using Skyla, 21.9% discontinued because of an adverse event. The most common adverse reactions were:

  • changes in bleeding patterns
  • vulvovaginitis
  • abdominal or pelvic pain
  • acne or seborrhea
  • ovarian cyst
  • headache.

3-Can Skyla IUD affect the period?

Your menstrual may become irregular, and the number of bleeding days may rise over the first 3 to 6 months. During this period, some women have excessive bleeding. You may also have spotting or mild bleeding regularly.

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